項聖謨（1597年 - 1658年），字孔彰，號易庵，浙江承宣布政使司嘉興府秀水縣（今浙江省嘉興市），明末清初畫家。

項聖謨為項元汴之孫，早年學習文學，後因此擅長古學，董其昌稱其的作品有宋元之氣。其有子項奎，字東井。存有《朗雲堂集》、《清河草堂集》。風格屬吳門畫派。

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Xiang Shengmo (項聖謨 Xiàng Shèngmó); (1597–1658) was a noted Chinese painter in the Ming Dynasty. He was a native of Xiushui (now Jiaxing, Zhejiang Province).

His courtesy name was Kongzhang (孔彰) and his art names were Yi'an (易庵), and Xushan Qiao (胥山樵). He was the grandson of the great painting-collector Xiang Yuanbian (項元汴). Xiang's painting followed the style of Wen Zhengming. Xiang specialized in landscapes and flowers with an elegant taste.