杜文秀（1823年 - 1872年），本名楊秀，字雲煥，號百香，回民，大清雲南省永昌府治保山縣金雞村人，清朝雲南回變首領，領導了清末的雲南回族穆斯林起義。

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Du Wenxiu (杜文秀 Dù Wénxiù|w=Tu Wen-hsiu, Xiao'erjing: ) (1823 to 1872) was the Chinese Muslim leader of the Panthay Rebellion, an anti-Qing revolt in China during the Qing dynasty. Du had Han Chinese ancestry.

Born in Yongchang (now Baoshan, Yunnan), Du Wenxiu was the son of a Han Chinese who converted to Islam. His original name was Yang Xiu (杨秀). He styled himself "Sultan of Dali" and reigned for 16 years before Qing troops under Cen Yuying beheaded him after he swallowed a ball of opium. His body is entombed in Xiadui.

The rebellion started after massacres of Hui perpetrated by the Qing authorities. Du used anti-Manchu rhetoric in his rebellion against the Qing, calling for Han to join the Hui to overthrow the Manchu-led Qing dynasty after 200 years of their rule. Du invited the fellow Hui Muslim leader Ma Rulong to join him in driving the Manchus out and "recover China". For his war against Manchu "oppression", Du "became a Muslim hero", while Ma Rulong defected to the Qing. On multiple occasions Kunming was attacked and sacked by Du Wenxiu's forces. He was the father of Du Fengyang, who also participated in the rebellion.

In Kunming, there was a slaughter of 3,000 Muslims on the instigation of the judicial commissioner, who was a Manchu, in 1856. Du Wenxiu was of Han Chinese origin despite being a Muslim and he led both Hui Muslims and Han Chinese in his civil and military bureaucracy. Du Wenxiu was fought against by another Muslim leader who defected to the Qing dynasty, Ma Rulong. The Muslim scholar Ma Dexin, who said that Neo-Confucianism was reconcilable with Islam, approved of Ma Rulong defecting to the Qing and he also assisted other Muslims in defecting.

Tribal pagan animism, Confucianism and Islam were all legalized and "honoured" with a "Chinese-style bureaucracy" in Du Wenxiu's sultanate. A third of the sultanate's military posts were filled with Han Chinese, who also filled the majority of civil posts.

His capital was Dali. The revolt ended in 1873. Du Wenxiu is regarded as a hero by the present day government of China.

Du Wenxiu's life and related historical facts are a major element of Tariq Ali's novel Night of the Golden Butterfly.